Stem Cell Therapies for Knee Cartilage Repair
نویسندگان
چکیده
منابع مشابه
Stem cell therapies for knee cartilage repair: the current status of preclinical and clinical studies.
BACKGROUND Articular cartilage damage of the knee is common, causing significant morbidity worldwide. Many adult tissues contain cells that are able to differentiate into multiple cell types, including chondrocytes. These stem cells have gained significant attention over the past decade and may become frontline management for cartilage defects in the very near future. PURPOSE The role of stem...
متن کاملCurrent perspectives in stem cell research for knee cartilage repair
Protocols based on the delivery of stem cells are currently applied in patients, showing encouraging results for the treatment of articular cartilage lesions (focal defects, osteoarthritis). Yet, restoration of a fully functional cartilage surface (native structural organization and mechanical functions) especially in the knee joint has not been reported to date, showing the need for improved d...
متن کاملChondrocyte and mesenchymal stem cell-based therapies for cartilage repair in osteoarthritis and related orthopaedic conditions.
Osteoarthritis (OA) represents a final and common pathway for all major traumatic insults to synovial joints. OA is the most common form of degenerative joint disease and a major cause of pain and disability. Despite the global increase in the incidence of OA, there are no effective pharmacotherapies capable of restoring the original structure and function of damaged articular cartilage. Conseq...
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لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملDevelopment and Application of Mesenchymal Stem Cell-derived Exosomes in Cartilage Tissue Repair
Background and Aim: Cartilage defects treatment is one of the most common clinical challenges in orthopedics. The current management techniques help to control symptom and joint function. The cell-free approach to cartilage regeneration through paracrine action has been considered to accelerate and facilitate the healing process and the importance of its urgency in the recovery of military pe...
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ژورنال
عنوان ژورنال: The American Journal of Sports Medicine
سال: 2013
ISSN: 0363-5465,1552-3365
DOI: 10.1177/0363546513508744